While it is generally considered safe for most people when taken in appropriate doses, there are certain situations where it may not be advisable to take ginkgo. If you are allergic to ginkgo or any of its components, you should avoid taking it, as it may cause an allergic reaction. If you are taking anticoagulant medications like warfarin, aspirin, or other blood thinners, it's important to consult with your healthcare provider before taking ginkgo. Ginkgo can interact with certain medications, including anticoagulants, antiplatelet drugs, antidepressants, anticonvulsants, and some medications metabolized by the liver. Consult your healthcare provider if you're taking any medications to ensure there are no potential interactions. Pregnancy and breastfeeding, there is limited research on the safety of ginkgo during pregnancy or while breastfeeding. As a precaution, it's generally recommended to avoid ginkgo in these situations.